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Martina Rahmeh Selected Research

Nelfinavir (Viracept)

12/2013Nelfinavir and bortezomib inhibit mTOR activity via ATF4-mediated sestrin-2 regulation.
10/2012Inhibin beta E is upregulated by drug-induced endoplasmic reticulum stress as a transcriptional target gene of ATF4.
1/2010The mitochondria-independent cytotoxic effect of nelfinavir on leukemia cells can be enhanced by sorafenib-mediated mcl-1 downregulation and mitochondrial membrane destabilization.
2/2009Nelfinavir induces the unfolded protein response in ovarian cancer cells, resulting in ER vacuolization, cell cycle retardation and apoptosis.
12/2008Nelfinavir induces TRAIL receptor upregulation in ovarian cancer cells.

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Martina Rahmeh Research Topics

Disease

8Neoplasms (Cancer)
02/2021 - 02/2006
3Breast Neoplasms (Breast Cancer)
01/2019 - 02/2006
3Ovarian Neoplasms (Ovarian Cancer)
12/2009 - 12/2008
2Habitual Abortion (Recurrent Miscarriage)
08/2021 - 11/2020
1Carcinogenesis
01/2019
1Endometrial Neoplasms (Endometrial Cancer)
01/2018
1Hepatocellular Carcinoma (Hepatoma)
10/2012
1Uterine Cervical Neoplasms (Cancer of the Cervix)
10/2012
1Hepatoblastoma
10/2012
1Leukemia
01/2010
1HIV Infections (HIV Infection)
02/2009
1Ascites
02/2009
1Necrosis
12/2008

Drug/Important Bio-Agent (IBA)

5Nelfinavir (Viracept)FDA Link
12/2013 - 12/2008
5Pharmaceutical PreparationsIBA
12/2013 - 12/2008
4Dinoprostone (PGE2)FDA Link
08/2021 - 01/2018
2Proteins (Proteins, Gene)FDA Link
01/2019 - 01/2010
2Carboplatin (JM8)FDA LinkGeneric
12/2009 - 02/2009
2TNF-Related Apoptosis-Inducing Ligand ReceptorsIBA
12/2009 - 12/2008
2HIV Protease InhibitorsIBA
02/2009 - 12/2008
1Sialic Acid Binding Immunoglobulin-like LectinsIBA
02/2021
1Mucin-1 (CA 15-3 Antigen)IBA
02/2021
1Galectins (Galectin)IBA
02/2021
1Estrogen ReceptorsIBA
02/2021
1CytokinesIBA
11/2020
1Messenger RNA (mRNA)IBA
01/2019
1Prostaglandin Receptors (Prostaglandin Receptor)IBA
01/2018
1Biomarkers (Surrogate Marker)IBA
01/2018
1ThapsigarginIBA
10/2012
1TunicamycinIBA
10/2012
1Inhibins (Inhibin)IBA
10/2012
1Sorafenib (BAY 43-9006)FDA Link
01/2010
1CaspasesIBA
01/2010
1Paclitaxel (Taxol)FDA LinkGeneric
12/2009
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
12/2009
1Bortezomib (Velcade)FDA Link
12/2009
1LigandsIBA
12/2009
1Protease Inhibitors (Protease Inhibitor)IBA
02/2009
1Endoplasmic Reticulum Chaperone BiPIBA
02/2009
1Proteasome InhibitorsIBA
02/2009
1Propidium (Propidium Iodide)IBA
12/2008
1AnnexinsIBA
12/2008
1Lapatinib (GW572016)FDA Link
02/2006
1Biological ProductsIBA
02/2006
1Trastuzumab (Herceptin)FDA Link
02/2006
1Phosphotransferases (Kinase)IBA
02/2006

Therapy/Procedure

1Therapeutics
01/2018